TARIFFS LATEST US, China to slash tariffs for 90 days Hamburg - Delayed Quote • EUR Roche Holding AG (RHO5.HM) Follow Add holdings 264.80 -10.40 (-3.78%) As of 12:37:08 PM GMT+2. Market Open. All News Press Releases SEC Filings Roche and Genentech Announce New North Carolina Manufacturing Facility SOUTH SAN FRANCISCO, Calif., May 12, 2025--Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today plans to invest more than $700 million in a new 700,000 square foot state-of-the-art drug manufacturing facility in Holly Springs, NC. Global Pharma Stocks Fall as Trump Plans to Cut Drug Prices Novo Nordisk, which generates around 60% of its sales in the U.S., is among the biggest losers in early European trade. Trump is hailing $2 trillion in new company investments. Most of it comes from Big Tech. President Trump has touted $2 trillion in new company investments since Inauguration Day. The lion's share comes from Big Tech, according to a Yahoo Finance analysis. Prothena Q1 Earnings Miss Estimates, Focus on Key Readouts in 2025 PRTA posts a wider-than-expected first-quarter loss. Investors will focus on important readouts on birtamimab and PRX012 later in 2025. Zealand Pharma AS (ZLDPF) Q1 2025 Earnings Call Highlights: Strategic Collaborations and ... Zealand Pharma AS (ZLDPF) reports robust financials and transformative partnerships, setting the stage for future growth in the obesity and rare disease markets. SRPT Q1 Earnings Miss, Sales Beat, Stock Slides 21% on '25 View Cut SRPT reports mixed first-quarter 2025 results. The stock plunges after the company significantly lowers its 2025 sales guidance. Roche introduces diagnostic test for liver fibrosis severity assessment The test operates on Roche's cobas analysers and requires one assay, delivering outcomes in 18 minutes. Roche introduces innovative Elecsys PRO-C3 test to improve precision in evaluating liver fibrosis severity Elecsys PRO-C3, used with the ADAPT formula (age, diabetes status, PRO-C3, platelets), assesses liver fibrosis severity – a disease responsible for approximately one in every 25 deaths worldwide1The test delivers results in just 18 minutes on Roche’s cobas analysers, providing a fast and reliable diagnostic method.The test enables earlier identification of patients with significant liver fibrosis, potentially improving outcomes through timely management and access to emerging therapies. Basel, 0 'Declare victory and move on': Eli Lilly CEO on Trump tariff threat Eli Lilly CEO says Trump tariff threat has already achieved the goal of repatriating manufacturing in pharma. CHMP recommends EU label update for Roche’s Phesgo to allow administration outside of clinical settings Positive recommendation based on clinical, real-world and bioequivalence data supporting feasibility and safety of Phesgo’s administration outside of clinical settings, for example at home1-4 Phesgo label expansion delivers on patients’ preference for at-home administration and is an important step in freeing up cancer care capacity in clinical settings3Phesgo has the potential to reduce treatment administration costs by up to 80% in Western Europe, and 85% of patients prefer SC over IV administ Roche granted FDA Breakthrough Device Designation for first AI-driven companion diagnostic for non-small cell lung cancer The VENTANA TROP2 (EPR20043) RxDx Device is an immunohistochemistry (IHC) assay combined with a digital pathology algorithm to determine patient treatment. The device uses artificial intelligence-based image analysis with a level of diagnostic precision not possible with traditional manual scoring methods. This Breakthrough Device Designation (BDD) demonstrates Roche’s continued innovation in companion diagnostics and digital pathology to enable more precise diagnosis in oncology. Basel, 29 Apri New England Journal of Medicine Publishes Phase III Data Showing Single-dose Xofluza Significantly Reduces Influenza Virus Transmission SOUTH SAN FRANCISCO, Calif., April 25, 2025--Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY) announced today that the New England Journal of Medicine (NEJM) has published a detailed analysis of the Phase III CENTERSTONE trial of Xofluza® (baloxavir marboxil). The trial met its primary endpoint, showing a single, oral dose of Xofluza taken by people infected with influenza reduced the odds of untreated household members contracting the virus by 32%. For the key secondary endpo Roche Sales Gain on Boost From Key Drugs Amid U.S. Production Push Roche posted higher-than-expected first-quarter sales, driven by robust demand for its key drugs, as the company takes active steps to preempt looming U.S. import tariffs. [Ad hoc announcement pursuant to Art. 53 LR] Roche continues good momentum into 2025 with 6% (CER) sales growth in the first quarter Group sales grew by 6%1 at constant exchange rates (CER; 7% in CHF), driven by high demand for newer medicines and diagnostic solutions.Pharmaceuticals Division sales rose by 8% (9% in CHF) on continued strong demand for a broad range of our medicines; top growth drivers were Phesgo (breast cancer), Vabysmo (severe eye diseases), Xolair (allergies) and Hemlibra (haemophilia A).Diagnostics Division sales remained stable with high demand across products and regions offsetting the impact of the rec Roche receives CE Mark for its Chest Pain Triage algorithm to enhance detection of Acute Coronary Syndrome (ACS) Roche, in collaboration with Universitätsklinikum Heidelberg, has developed a Chest Pain Triage algorithm – a CE-marked IVD medical device1 set to transform cardiac careThis novel algorithm offers a standardised assessment, helping emergency room doctors to make confident clinical decisions in ruling in or ruling out heart attacks (acute myocardial infarction)Cardiovascular disease causes a third of worldwide deaths2, with chest pain being the second highest reason for emergency department (ED) Drug Companies Step Up 'Make in America' Plans to Counter Tariffs Drugmakers Roche and Regeneron said they will spend billions of dollars to expand U.S. manufacturing, the latest pharmaceutical companies to commit to American production as new and future tariffs loom over medicines made abroad. Regeneron, which makes drugs for skin and respiratory diseases, is doubling its U.S. manufacturing capacity in a new $3 billion, 10-year agreement with Fujifilm Diosynth Biotechnologies. Fujifilm’s plant in Holly Springs, N.C., will make bulk drug material for Regeneron medicines. Trending tickers: Nvidia, Tesla, Roche, Novo Nordisk and Fresnillo The latest investor updates on stocks that are trending on Tuesday. Roche, Apple, TSMC: Tracking Corporate Spending Pledges Under Trump Swiss drugmaker Roche unveiled a $50 billion plan to invest in the U.S., adding to a series of commitments by big corporations. 🚢 CMA CGM: The French shipping company aims to invest $20 billion in the U.S., creating 10,000 jobs. CMA CGM will triple its U.S.-flagged fleet, upgrade port facilities and create a Chicago airfreight hub. 💉 Eli Lilly: The drugmaker behind Zepbound and Mounjaro plans to invest $27 billion building four manufacturing plants in the U.S. Lilly expects the project will employ 10,000 construction workers. Roche to Invest $50 Billion in U.S. Manufacturing, R&D as Tariffs Loom The pharma giant said the investment would create more than 12,000 jobs, as it joins rival Novartis in expanding its footprint in the country amid President Trump’s tariff threats. Roche to invest USD 50 billion in pharmaceuticals and diagnostics in the United States over the next five years USD 50 billion commitment includes new state-of-the art research and development (R&D) sites, new and expanded manufacturing facilities in Indiana, Pennsylvania, Massachusetts and California and an additional site location to be announced soonInvestments will create more than 12,000 new jobs: 1,000 at Roche and more than 11,000 in support of new US manufacturing capabilities Roche already has a significant existing US presence with more than 25,000 employees, 15 R&D centres and 13 manufacturing Performance Overview Trailing total returns as of 5/12/2025, which may include dividends or other distributions. Benchmark is MSCI WORLD (^990100-USD-STRD) Return RHO5.HM MSCI WORLD (^990100-USD-STRD) YTD +12.27% -0.39% 1-Year +12.27% +8.31% 3-Year +21.55% +39.65%