Stock market news live updates: S&P 500 loses gains after report says Pfizer is contending with vaccine supply chain issues

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The S&P 500 erased earlier gains and ended Thursday’s session slightly negative after a report emerged that Pfizer was contending with supply-chain issues that would impact this year’s deliveries of its COVID-19 vaccine. The Nasdaq, however, managed to eke out a record closing high.

[Click here to read what’s moving markets heading into Friday, Dec. 4]

The Wall Street Journal reported Thursday afternoon that the drug-maker expects to ship just half of the COVID-19 vaccines it had planned for 2020 due to problems with its supply chain, or 50 million as opposed to the 100 million it previously said it would deliver. However, the company reportedly anticipates handing over more than a billion doses in 2021. Shares of Pfizer sank nearly 2% amid the news.

Earlier this week, more upbeat news came out around drugmakers’ coronavirus vaccines, though these did not trigger the outsized moves higher in the broader market seen last month. Britain became the world’s first country to grant emergency authorization for Pfizer and BioNTech’s COVID-19 vaccine and is set to begin shots within days. Though emergency use authorization of the vaccine is still being reviewed in the U.S. by the Food and Drug Administration, officials have expressed optimism about first doses getting rolled out in the middle of December.

Still, Americans will continue to contend with the coronavirus pandemic in the meantime until the vaccine becomes available on a widespread basis. Robert Redfield, The Centers for Disease Control and Prevention director, said during a virtual event Wednesday that December, January and February are likely “going to be the most difficult in the public health history of this nation, largely because of the stress that’s going to be put on our health-care system.” He added that COVID-19 deaths could total nearly 450,000 in the U.S. in February, rising rapidly from the more than 270,000 reported to date.

With a tough winter left to endure, some lawmakers have amplified calls to pass another round of fiscal stimulus before year-end. House Speaker Nancy Pelosi and Senate Democratic Leader Chuck Schumer each said they supported a bipartisan group of lawmakers’ recently unveiled $908 billion stimulus proposal, despite the sum being less than the $2 trillion package the Democratic lawmakers had sought previously. President-elect Joe Biden also endorsed the bill, and suggested that it would be the start of a more comprehensive suite of relief legislation once he is inaugurated in January.

Markets, however, have been bracing for a stimulus package for months, and many economists have baked in expectations of further fiscal stimulus into their baseline outlooks for U.S. economic activity. That may leave little further upside for equities to trade around stimulus news, unless the eventual legislation is much larger in size and scope than currently anticipated, according to some analysts.