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Denali Therapeutics Inc. (4DN.MU)

12.82
+0.09
+(0.75%)
At close: 8:01:43 AM GMT+2
Loading Chart for 4DN.MU
  • Previous Close 12.73
  • Open 0.00
  • Bid --
  • Ask --
  • Day's Range 0.00 - 0.00
  • 52 Week Range 0.00 - 29.49
  • Volume 0
  • Avg. Volume 21
  • Market Cap (intraday) 1.874B
  • Beta (5Y Monthly) 1.49
  • PE Ratio (TTM) --
  • EPS (TTM) -2.38
  • Earnings Date Jul 30, 2025 - Aug 4, 2025
  • Forward Dividend & Yield --
  • Ex-Dividend Date --
  • 1y Target Est --

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.

www.denalitherapeutics.com

443

Full Time Employees

December 31

Fiscal Year Ends

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Performance Overview: 4DN.MU

Trailing total returns as of 5/12/2025, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

4DN.MU
35.32%
S&P 500 (^GSPC)
0.64%

1-Year Return

4DN.MU
26.62%
S&P 500 (^GSPC)
11.90%

3-Year Return

4DN.MU
35.56%
S&P 500 (^GSPC)
48.70%

5-Year Return

4DN.MU
44.07%
S&P 500 (^GSPC)
103.62%

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Statistics: 4DN.MU

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Valuation Measures

Annual
As of 5/9/2025
  • Market Cap

    1.86B

  • Enterprise Value

    1.17B

  • Trailing P/E

    --

  • Forward P/E

    --

  • PEG Ratio (5yr expected)

    --

  • Price/Sales (ttm)

    --

  • Price/Book (mrq)

    1.85

  • Enterprise Value/Revenue

    --

  • Enterprise Value/EBITDA

    --

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -22.58%

  • Return on Equity (ttm)

    -35.21%

  • Revenue (ttm)

    --

  • Net Income Avi to Common (ttm)

    -453.94M

  • Diluted EPS (ttm)

    -2.38

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    817.93M

  • Total Debt/Equity (mrq)

    4.59%

  • Levered Free Cash Flow (ttm)

    -257.29M

Research Analysis: 4DN.MU

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